Have your chimneys swept often if you burn wood in your home. The more often, the better, regardless of amount of use. Smoldering fire, moist fire wood, and heavy use of dampers can lead to quicker buildup of creosote, potentially leading to a chimney fire. When unused, animals and debris can also clog your chimneys, which can lead to a chimney fire.
Clean out the lint in dryer duct work to help reduce risk of fire.
Make sure your smoke detectors are in good working order and have fresh batteries. It is best to have hardwired smoke detectors with a battery backup.
Consider installing a carbon monoxide detector, especially if you have a gas oven/stove, any type of wood or gas fireplace, a garage where vehicles or equipment could be left idling inside, etc.
Have one or more fire extinguishers in your home and vehicles that are checked annually and in good working order.